Population PK/Pharmacometrics Modeler (Oncology)

About the role

We are looking for a proactive pharmacometrician to join our Pharmacokinetics and Toxicology team in Toulouse. You will translate clinical trial data into strategic insights that shape dosing strategies, trial designs, and regulatory submissions for oncology programs.

Key responsibilities

• Lead population PK/PD modeling strategies and provide clear recommendations for clinical development decisions.
• Develop and qualify pharmacometrics analyses, focusing on exposure‑response relationships in oncology.
• Integrate pharmacometrics analyses early in the drug development process to mitigate risks.
• Identify opportunities to improve understanding of pharmacokinetics, pharmacodynamics, safety, and efficacy.
• Author and contribute to pharmacometrics sections of clinical and regulatory documents.
• Represent the team at global regulatory hearings and advisory committee meetings.
• Mentor colleagues on pharmacometrics methodology and support scientific publications.

Required profile

• PhD in Pharmaceutical Sciences, Pharmacometrics, Biostatistics, Applied Mathematics, or a related quantitative field.
• Minimum 5 + years of hands‑on population PK modeling experience in the pharmaceutical industry.
• Expert‑level proficiency with NONMEM; familiarity with Monolix is a plus.
• Extensive experience with advanced population PK/PD methodology and exposure‑response analysis.
• Strong programming skills in R or Python for data manipulation, diagnostics, and visualization.

Required skills

• NONMEM
• Monolix (optional)
• R programming
• Python programming
• Population PK/PD modeling
• Exposure‑response analysis

What we offer

• Attractive remuneration package with incentives, profit‑sharing, and Pierre Fabre shareholding.
• Health and provident insurance.
• 16 days of RTT plus 25 personal holidays.
• Public transport participation.
• Hybrid work mode with up to 2 days of teleworking per week.